Following on from our e-symposium, ‘Nutrition, Lifestyle and Menopause’ we’ve pulled together some of the key resources and references discussed within the webinar. If you missed the live webinar, you can register to watch the recording.

SESSION: OPENING REMARKS BY PROFESSOR NICK PANAY

 @hormonehealthuk

Guidelines/Studies/Resources

Hickey M, LaCroix AZ, Doust J, Mishra GD, Sivakami M, Garlick D, Hunter MS. An empowerment model for managing menopause. Lancet. 2024 Mar 9;403(10430):947-957.

Nappi RE, Panay N, Davis SR. In search of a well-balanced narrative of the menopause momentum. Climacteric. 2024 Jun;27(3):223-225.

Panay N, Ang SB, Cheshire R, et al. Menopause and MHT in 2024: addressing the key controversies – an International Menopause Society White Paper. Climacteric. 2024;27(5):441-457. doi:10.1080/13697137.2024.2394950

SESSION: MENOPAUSE 101 BY DR KATIE BARBER

Melissa Mogor

 @oxford_menopause

Guidelines/Studies/Resources

Meczekalski B, Podfigurna A, Czyzyk A, et al. Premature ovarian insufficiency: A comprehensive review. J Clin Med. 2023;12(12):4042. doi:10.3390/jcm12124042. Accessed March 24, 2025. https://thebms.org.uk/wp-content/uploads/2024/04/05-BMS-ConsensusStatement-Premature-ovarian-insufficiency-POI-APRIL2024-C.pdf

National Institute for Health and Care Excellence (NICE). Menopause: Identification and Management. NICE Guideline [NG23]. Published November 12, 2015. Updated November 7, 2024. Accessed March 24, 2025. https://www.nice.org.uk/guidance/ng23

Meczekalski B, et al. Premature ovarian insufficiency (POI). J Clin Med. 2023;12(12):4042. Accessed April 2024. https://thebms.org.uk/wp-content/uploads/2024/04/05-BMS-ConsensusStatement-Premature-ovarian-insufficiency-POI-APRIL2024-C.pdf.

Salpeter SR, Walsh JME, Greyber E, Salpeter EE. Hormone therapy and mortality in younger postmenopausal women: a meta-analysis. J Gen Intern Med. 2006;21:363-366.

Hodis HN, Mack WJ. Effects of hormone therapy on cancer risk: current evidence and future directions. Cancer J. 2022;28(3):208-223.

Women’s Health Concern – womens-health-concern.org

Menopause matters – menopausematters.co.uk/

Frax calculator – https://www.fraxplus.org/calculation-tool

SESSION: NUTRITION CONSIDERATIONS IN MENOPAUSE BY NIGEL DENBY 

Melissa Mogor

 @menopause_dietitian   @menopause_dietitian

Guidelines/Studies/Resources

Academy of Nutrition and Dietetics. What is Intermittent Fasting? Available at: https://www.eatright.org/health/wellness/diet-trends/what-is-intermittent-fasting. Accessed March 25, 2025.

Academy of Nutrition and Dietetics. What is the Ketogenic Diet? Available at: https://www.eatright.org/health/wellness/diet-trends/what-is-the-ketogenic-diet. Accessed March 25, 2025.

Barrea L, Pugliese G, Laudisio D, Colao A, Savastano S, Muscogiuri G. Mediterranean diet as a medical prescription in menopausal women with obesity: A practical guide for nutritionists. Crit Rev Food Sci Nutr. 2021;61(7):1201-1211. doi:10.1080/10408398.2020.1755220. Epub 2020 Apr 24. PMID: 32329636.

British Dietetic Association (BDA). Medical Ketogenic Diets. Available at: https://www.bda.uk.com/resource/medical-ketogenic-diets.html. Accessed March 25, 2025.

British Menopause Society. 06-BMS-ConsensusStatement-Prevention-and-treatment-of-osteoporosis-in-women-SEPT2023-A.pdf.

Erdélyi A, Pálfi E, Tűű L, Nas K, Szűcs Z, Török M, Jakab A, Várbíró S. The importance of nutrition in menopause and perimenopause—A review. Nutrients. 2023 Dec 21;16(1):27. doi:10.3390/nu16010027. PMID: 38201856; PMCID: PMC10780928.

Fenton A, Smart C, Goldschmidt L, Price V, Scott J. Fat mass, weight and body shape changes at menopause—causes and consequences: a narrative review. Climacteric. 2023 Aug;26(4):381-387. doi:10.1080/13697137.2023.2178892. Epub 2023 Mar 9. PMID: 36891919.

Hurtado MD, Saadedine M, Kapoor E, Shufelt CL, Faubion SS. Weight gain in midlife women. Curr Obes Rep. 2024 Jun;13(2):352-363. doi:10.1007/s13679-024-00555-2. Epub 2024 Feb 28. PMID: 38416337; PMCID: PMC11150086.

National Institute for Health and Care Excellence (NICE). Menopause: Diagnosis and Management. Updated November 2024. Accessed March 25, 2025.

National Institute for Health and Care Excellence (NICE). Weight management: lifestyle services for overweight or obese adults. 2022. Available at: www.nice.org.uk. Accessed March 25, 2025.

Study of Women’s Health Across the Nation (SWAN). Menopause and body composition changes. Available at: SWAN Official Website. Accessed March 25, 2025.

Barrea L, Pugliese G, Laudisio D, Colao A, Savastano S, Muscogiuri G. Mediterranean diet as a medical prescription in menopausal women with obesity: A practical guide for nutritionists. Crit Rev Food Sci Nutr. 2021;61(7):1201-1211. doi:10.1080/10408398.2020.1755220. Epub 2020 Apr 24. PMID: 32329636.

British Dietetic Association (BDA). Medical Ketogenic Diets. Available at: https://www.bda.uk.com/resource/medical-ketogenic-diets.html. Accessed March 25, 2025.

British Menopause Society. 06-BMS-ConsensusStatement-Prevention-and-treatment-of-osteoporosis-in-women-SEPT2023-A.pdf.

Erdélyi A, Pálfi E, Tűű L, Nas K, Szűcs Z, Török M, Jakab A, Várbíró S. The importance of nutrition in menopause and perimenopause—A review. Nutrients. 2023 Dec 21;16(1):27. doi:10.3390/nu16010027. PMID: 38201856; PMCID: PMC10780928.

Fenton A, Smart C, Goldschmidt L, Price V, Scott J. Fat mass, weight and body shape changes at menopause—causes and consequences: a narrative review. Climacteric. 2023 Aug;26(4):381-387. doi:10.1080/13697137.2023.2178892. Epub 2023 Mar 9. PMID: 36891919.

Hurtado MD, Saadedine M, Kapoor E, Shufelt CL, Faubion SS. Weight gain in midlife women. Curr Obes Rep. 2024 Jun;13(2):352-363. doi:10.1007/s13679-024-00555-2. Epub 2024 Feb 28. PMID: 38416337; PMCID: PMC11150086.

National Institute for Health and Care Excellence (NICE). Effective Communication Guidelines. Updated November 2024. Accessed March 25, 2025.

National Institute for Health and Care Excellence (NICE). Menopause: Diagnosis and Management. Updated November 2024. Accessed March 25, 2025.

National Institute for Health and Care Excellence (NICE). Weight management: lifestyle services for overweight or obese adults. 2022. Available at: www.nice.org.uk. Accessed March 25, 2025.

Study of Women’s Health Across the Nation (SWAN). Menopause and body composition changes. Available at: SWAN Official Website. Accessed March 25, 2025.

SESSION: DIGESTIVE HEALTH ISSUES – A SYMPTOM OF PERIMENOPAUSE

Melissa Mogor

 @thecalmgutdietitian

Guidelines/Studies/Resources

Hungin APS, Mitchell CR, Whorwell P, Mulligan C, Cole O, Agréus L, Fracasso P, Lionis C, Mendive J, Philippart de Foy JM, Seifert B, Wensaas KA, Winchester C, de Wit N; European Society for Primary Care Gastroenterology. Systematic review: probiotics in the management of lower gastrointestinal symptoms – an updated evidence-based international consensus. Aliment Pharmacol Ther. 2018 Apr;47(8):1054-1070. doi: 10.1111/apt.14539. Epub 2018 Feb 20. PMID: 29460487; PMCID: PMC5900870.

Heitkemper, M.M. and Chang, L. (2009) ‘Do fluctuations in ovarian hormones affect gastrointestinal symptoms in women with irritable bowel syndrome?’ Gender Medicine, 6(Suppl 2), pp. 152-167. Available at: https://doi.org/10.1016/j.genm.2009.03.004.

Liu Y, Zhou Y, Mao T, Huang Y, Liang J, Zhu M, Yao P, Zong Y, Lang J, Zhang Y. The relationship between menopausal syndrome and gut microbes. BMC Womens Health. 2022 Nov 8;22(1):437. doi: 10.1186/s12905-022-02029-w. PMID: 36348390; PMCID: PMC9644609.

McFarland LV, Karakan T, Karatas A. Strain-specific and outcome-specific efficacy of probiotics for the treatment of irritable bowel syndrome: A systematic review and meta-analysis. EClinicalMedicine. 2021 Oct 18;41:101154. doi: 10.1016/j.eclinm.2021.101154. PMID: 34712929; PMCID: PMC8333249.

Nie, X., Xie, R. and Tuo, B. (2018) ‘Effects of estrogen on the gastrointestinal tract.’ Digestive Diseases and Sciences, 63(3), pp. 583-596. Available at: https://doi.org/10.1007/s10620-018-4939-1.

Santoro, N., Roeca, C., Peters, B.A. and Neal-Perry, G. (2021) ‘The menopause transition: Signs, symptoms, and management options.’ Journal of Clinical Endocrinology and Metabolism, 106(1), pp. 1-15. Available at: https://doi.org/10.1210/clinem/dgaa764.

Shang, X.; E, F.-F.; Guo, K.-L.; Li, Y.-F.; Zhao, H.-L.; Wang, Y.; Chen, N.; Nian, T.; Yang, C.-Q.; Yang, K.-H.; et al. Effectiveness and Safety of Probiotics for Patients with Constipation-Predominant Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of 10 Randomized Controlled Trials. Nutrients, 2022, 14, 2482. https://doi.org/10.3390/nu14122482.

Shieh, A., Epeldegui, M., Karlamangla, A.S. and Greendale, G.A. (2020) ‘Gut permeability, inflammation, and bone density across the menopause transition.’ JCI Insight, 5(2), pp. 30. Available at: https://doi.org/10.1172/jci.insight.134092.

Savarino E, Zingone F, Barberio B, Marasco G, Akyuz F, Akpinar H, Barboi O, Bodini G, Bor S, Chiarioni G, Cristian G, Corsetti M, Di Sabatino A, Dimitriu AM, Drug V, Dumitrascu DL, Ford AC, Hauser G, Nakov R, Patel N, Pohl D, Sfarti C, Serra J, Simrén M, Suciu A, Tack J, Toruner M, Walters J, Cremon C, Barbara G. Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility. United European Gastroenterol J. 2022 Jul;10(6):556-584. doi: 10.1002/ueg2.12259. Epub 2022 Jun 13. PMID: 35695704; PMCID: PMC9278595.

Yang M, Wen S, Zhang J, Peng J, Shen X, Xu L. Systematic Review and Meta-analysis: Changes of Gut Microbiota before and after Menopause. Dis Markers. 2022 Jul 25;2022:3767373. doi: 10.1155/2022/3767373. PMID: 35923245; PMCID: PMC9343210.

Zia, J.K. and Heitkemper, M.M. (2016) ‘Upper gastrointestinal tract motility disorders in women, gastroparesis, and gastroesophageal reflux disease.’ Gastroenterology Clinics of North America, 45(2), pp. 239-251. Available at: https://dx.doi.org/10.1016/j.gtc.2016.02.003.

SESSION: BONE HEALTH BY DR SARAH JARVIS

Dr Fabrice DeClerck Science Director, EAT

Guidelines/Studies/Resources

Eastell R, O’Neill T, Hofbauer L, et al. Postmenopausal osteoporosis. Nat Rev Dis Primers. 2016;2:16069. doi:10.1038/nrdp.2016.69.

National Institute for Health and Care Excellence (NICE). Osteoporosis – prevention of fragility fractures: prevalence. Accessed March 2025. Available at: https://cks.nice.org.uk/topics/osteoporosis-prevention-of-fragility-fractures/background-information/prevalence/

Pouresmaelili F, Kamalidehghan B, et al. Molecular mechanisms and biological functions of autophagy in cancer. Ther Clin Risk Manag. 2018;14:2029-2049. doi:10.2147/TCRM.S181539. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6225907/.

Royal Osteoporosis Society. The impact of osteoporosis: media toolkit. Accessed March 2025. Available at: https://theros.org.uk/about-us/media-centre/media-toolkit/#:~:text=The%20impact,1.1bn%20for%20social%20care

Royal Osteoporosis Society. Survey of ROS members (2023) analysed by Oxford University academics. Data available on request.

Svedbom A, Hernlund E, Ivergård M, et al.; EU Review Panel of IOF. Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos. 2013;8(1):137. doi:10.1007/s11657-013-0137-0.

SESSION: MENOPAUSE AND THE MIND BY DR ZOE SCHAEDEL

Dr Zoe Schaedel

Bonsignore MR, Saaresranta T, Riha RL. Eur Respir Rev. 2019;28:190030.

Bromberger J, et al. Menopause (New York, N.Y.). 2013;20(5):488–95. doi:10.1097/GME.0b013e3182730599.

Coslov N, et al. “Not Feeling like Myself” in Perimenopause — What Does It Mean? Observations from the Women Living Better Survey. Menopause. 2024;31(5):390. doi:10.1097/GME.0000000000002339.

De Kruif M, et al. Journal of Affective Disorders. 2016;206:174–80.

Graziottin A, Serafini A. Menopause International. 2009;15(2):76–81.

Alblooshi S, Taylor M, Gill N. Does Menopause Elevate the Risk for Developing Depression and Anxiety? Results from a Systematic Review. 2023.

Womens Health Concern. Complementary and alternative therapies.

National Institute for Health and Care Excellence (NICE). CKS Insomnia. 2024.

SESSION: CBT AND CBTI AS TREATMENTS FOR MENOPAUSAL SYMPTOMS BY DR MELANIE SMITH

Melissa Mogor

Balabanovic J, Ayers B, Hunter MS. Cognitive behaviour therapy for menopausal hot flushes and night sweats: a qualitative analysis of women’s experiences of group and self-help CBT. Behavioural and Cognitive Psychotherapy. 2013;41(4):441-457.

Carmona NE, Millett GE, Green SM, Carney CE. Cognitive-behavioural, behavioural and mindfulness-based therapies for insomnia in menopause. Behavioural Sleep Medicine. 2023;21(4):488-499.

Hunter M, Smith M. Managing Hot Flushes with Group Cognitive Behaviour Therapy. Routledge; 2015.

Ntikoudi A, Owens DA, Spyrou A, Evangelou E, Vlachou E. The Effectiveness of Cognitive Behavioural Therapy on Insomnia Severity Among Menopausal Women: A Scoping Review. Life. 2024;14(11):1405.

Ye M, Shou M, Zhang J, Hu B, Liu C, Bi C, et al. Efficacy of cognitive therapy and behaviour therapy for menopausal symptoms: a systematic review and meta-analysis. Psychological Medicine. 2022;52(3):433-445.

SESSION: CHOLESTEROL AND CVD RISK IN MENOPAUSE BY DR TINA KHAN

Melissa Mogor

British Heart Foundation. Analysis of Latest UK Mortality Statistics: ONS/NRS/NISRA (2017 Data). 2017.

CVDPREVENT. Deep Dive: Inequalities in Cholesterol Management by Sex for Patients with CVD. Office for Health Improvement & Disparities (OHID) and NHS Benchmarking Network; 2024.

Global Burden of Disease Study 2019. Institute for Health Metrics and Evaluation (IHME); 2020 [updated 21/02/2024]. Available at: https://www.healthdata.org/data-toolspractices/interactive-visuals/gbd-compare.

ONS. Deaths Registered in England and Wales: 2022. ONS; 2023.

Zhao M, Vaartjes I, Graham I, et al. Sex differences in risk factor management of coronary heart disease across three regions. Heart. 2017;103(20):1587-1594. doi: 10.1136/heartjnl-2017-311429. Epub 2017 Sep 20.

Yi SW, Yi JJ, Ohrr H. Total cholesterol and all-cause mortality by sex and age: a prospective cohort study among 12.8 million adults. Sci Rep. 2019;9:1596.

SESSION: DIETARY MANAGEMENT OF CHOLESTEROL BY DR LINIA PATEL

Dr Wendy Hall, PhD RNutr, Reader in Nutritional Sciences, Department of Nutritional Sciences, Faculty of Life Sciences & Medicine, King’s College London

 @liniapatelnutrition

British Dietetic Association. Heart health Fact sheet. Available at: https://www.bda.uk.com/resource/heart-health.html. Accessed March 25, 2025.

British Heart Foundation. Menopause and Heart Health. Available at: https://www.bhf.org.uk/informationsupport/heart-matters-magazine/nutrition/menopause-and-heart-health. Accessed March 25, 2025.

Estruch R, Ros E, Salas-Salvadó J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts. N Engl J Med. 2018;378(25):e34.Alliance UOregon+6PubMed+6Europe PMC+6

Jenkins DJ, Kendall CW, Marchie A, et al. Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein. JAMA. 2003;290(4):502-510.PubMed+3Unbound Medicine+3Nutrition Guide+3

Riechman SE, Andrews RD, Maclean DA, Sheather S. Statins and dietary and serum cholesterol are associated with increased lean mass following resistance training. Metabolism. 2007;56(7):976-983.

SESSION: A PILL FOR EVERY ILL BY KEVIN LEIVERS

Dr Wendy Hall, PhD RNutr, Reader in Nutritional Sciences, Department of Nutritional Sciences, Faculty of Life Sciences & Medicine, King’s College London

 @thenakedpharmacy

Lopresti, A.L., Smith, S.J. & Drummond, P.D., 2022. An investigation into an evening intake of a saffron extract on sleep quality, cortisol, and melatonin concentrations in adults with poor sleep: A randomised, double-blind, placebo-controlled, multi-dose study.

Gliozzi, M., et al., 2013. Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia.

YOUR MENOPAUSE BY HARLEY STREET AT HOME

Your Menopause by Harley Street at Home works exclusively with British Menopause Society-accredited specialist doctors to provide healthcare professionals with expert, evidence-based support.

SYMPROVE

Symprove is the #1 probiotic for healthcare professionals, recommended by gastroenterologists, GPs, dietitians and nutritionists.

HORMONE HEALTH

Hormone Health is a private women’s health clinic founded by Professor Nick Panay.

BDA Women’s Health and Fertility Specialist Group

The Women’s Health and Fertility Specialist Group Group are a specialist group of the British Dietetic Association. The ambitious and passionate group are dedicated to research, education and improving the standards and quality of care to patients accessing such services nationwide.

 @BdaMaternal   @bda_maternalandfertility

Resources:

  • Fertility Nutrition Course for Healthcare Professionals – by Fertility Dietitian UK – This course brings you the latest evidence-based information in the field of fertility nutrition, equipping you with the information you need to support your clinical practice. Sign up.
  • e nutrition and pregnancy course – mix of live and recorded sessions. Email maternalfertilitysg@bda.uk.com if interested.

LINWOODS

Linwoods is a leading provider of nutrient-rich, organic milled seeds, nuts, and blends, designed to support health and wellbeing.

 

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