Following on from our webinar ’Soy Isoflavones in the Endocrine System’, we’ve pulled together some of the key resources and references discussed within the webinar, plus some additional ones on the topic. We have also included useful websites and social media accounts recommended to keep up to date on the subject. If you missed the live webinar, you can watch the recording.

GUIDELINES AND REPORTS

The Future of Soya for Health and Sustainability Part 1 of 3 – Why consider soya alternatives to dairy and meat: building a healthy sustainable diet (2022). MyNutriWeb, Alpro Foundation and Fuji Foundation for Protein Research. Proceedings from the first of the three part series. Internationally-acclaimed experts present the latest research from across the globe

The health effects of soy: A reference guide for health professionals (2022). Messina M et al. Guide for health professionals to be used when discussing soyfoods with their clients and patients

Soya Nutrition, Health and Sustainability (2022). MyNutriWeb. The latest research and practical guidance on soya for human consumption

American Cancer Society nutrition and physical activity guideline for cancer survivors (2022). Rock C et al. Guidelines into lifestyle factors and cancer survivors including reducing recurrence

Soy: Intake does not increase risk for breast cancer survivors (2021). American Institute for Cancer Research (AICR). Guidance around soy from the AICR

Diet, nutrition, physical activity and breast cancer (2018). World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR). Continuous Update Project Expert Report 2018

Male soy food intake was not associated with in vitro fertilization outcomes among couples attending a fertility center (2015).  Mínguez-Alarcón L et al. In this cohort of men from subfertile couples presenting to a fertility clinic, men’s intake of soy foods and soy isoflavones was unrelated to treatment outcomes

Soy protein isolates of varying isoflavone content do not adversely affect semen quality in healthy young men (2010). Beaten L et al. Supporting no adverse effects of soy on male fertility

Report on the 8th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment (2009). Messina M et al. Major findings from the International Symposium on Soy presented – supports no adverse effects of soy or isoflavones on sperm or semen parameters

RESEARCH PAPERS

Soy isoflavone metabolite equol inhibits cancer cell proliferation in a PAP associated domain containing 5-dependent and an estrogen receptor-independent manner (2022). Yamashita S. Study demonstrating the anti-cancer effects of soy isoflavones

Neither soyfoods nor isoflavones warrant classification as endocrine disruptors: a technical review of the observational and clinical data (2021). Messina M et al. Effects of soy mediated by isoflavones

Neither soy nor isoflavone intake affects male reproductive hormones: An expanded and updated meta-analysis of clinical studies (2021). Reed K et al. Study finding no effects of soy or soy isoflavones on hormone levels in men

Effect of the Intake of Isoflavones on Risk Factors of Breast Cancer—A Systematic Review of Randomized Controlled Intervention Studies (2021). Finkeldey L et al. Systematic review finding that there is little evidence that isoflavone treatment modulates risk factors of breast cancer in pre- and postmenopausal women

Association of soy and fermented soy product intake with total and cause specific mortality: prospective cohort study (2020). Katagiri R et al. Study in the BMJ showing the higher the total fermented soy product intake, the lower the total mortality in men and women

Dietary isoflavones or isoflavone-rich food intake and breast cancer risk: A meta-analysis of prospective cohort studies (2019). Zhao Ting-Ting et al. Meta-analysis indicating that women with a high dietary intake of soy foods may experience a reduction in breast cancer risk

The effects of green kiwifruit combined with isoflavones on equol production, bone turnover and gut microflora in healthy postmenopausal women (2018). Kruger et al. Study showing the benefits of kiwifruit (green) combined with isoflavones on equol production, possibly due to the vitamin K1

Does high dietary soy intake affect a woman’s risk of primary or recurrent breast cancer? (2015). Eakin A et al. Evidence based summary concluding that soy  doesn’t affect the risk of primary breast cancer, but it does (favorably) affect the risk of cancer recurrence.

Is soy intake related to age at onset of menarche? A cross-sectional study among adolescents with a wide range of soy food consumption (2014). Gina Segovia-Siapco. Study finding that soy intake is not associated with age at onset of menarche in a population of adolescent girls

Post-diagnosis soy food intake and breast cancer survival (2013). Chi F et al. Meta-analysis of cohort studies which showed that soy food intake might be associated with better survival, especially for ER negative, ER+/ PR+, and postmenopausal patients.

Progression From High-Grade Prostatic Intraepithelial Neoplasia to Cancer: A Randomized Trial of Combination Vitamin-E, Soy, and Selenium (2011). Fleshner et al. Study finding supporting no evidence of gynecomastia from soy intake

Natural S-equol decreases bone resorption in postmenopausal, non-equol-producing Japanese women: a pilot randomized, placebo-controlled trial (2011). Tousen Y et al. Study finding that 10 mg/day of natural S-equol supplementation contributes to bone health in non-equol-producing postmenopausal women without adverse effects

Soy food and isoflavone intake in relation to semen quality parameters among men from an infertility clinic (2008). Chavarro J. Data which suggests that higher intake of soy foods and soy isoflavones is associated with lower sperm concentration – many limitations of the research as noted in the webinar

Meta-analysis of the effects of soy protein intake on serum lipids (1995). Anderson JW et al. Data concerning the beneficial intake of soy intake on fat and bone metabolism – meta-analysis of 38 reports showing that animal protein replaced with soy protein in the diet resulted in benefits for lipid profile

PRACTICAL RESOURCES

Questions and Answers: Fuji and Alpro Soya Symposium Series 1 of 3 (2022). MyNutriWeb, Alpro Foundation and Fuji Foundation for Protein Research. Q&As from the first of the three part series on the future of soy

The Eatwell Guide (2019). The National Health Service (NHS). Practical guide to healthy eating

Soya Foods and Your Health (2019). The British Dietetic Association. Food fact sheet

The Composition of Foods 7th Edition. (2014). McCance & Widdowson. Composition of foods, including soya composition

Dairy and alternatives in your diet. NHS. Dietary information including soya as an alternative to dairy foods

Soy. The Vegan RD. Lots of useful practical information around soy foods

ALPRO FOUNDATION & FUJI FOUNDATION FOR PROTEIN RESEARCH

Alpro Foundation

Fuji Foundation for Protein Research

RELATED MYNUTRIWEB CONTENT

Part 1 of 3 – Why Consider Soy Alternatives to Dairy and Meat (2022). This event is the part one of the three-part webinar series on The Future of Soya for Health and Sustainability – Sharing Global Learnings. Part one of the series provides an overview of the latest significant peer-reviewed research papers on soy, and why we should be including soy dairy and meat alternatives in a healthy sustainable diet for both adults and children.  Supporting resource blog

Shifting Food Systems (2021). E-symposium with leading experts about sustainable eating, including a practical interview on transitioning towards a plant-based diet and supporting resource blog

Changing Behaviours: From Policy to Table (2021) – Half day e-symposium looking into sustainable eating and the role of behaviour change and supporting resource blog

ROUNDTABLE ON SOYA NUTRITION HEALTH AND SUSTAINABILITY (2021). Internationally acclaimed expert panel of academics, doctors, and nutritionists discussing the very latest research in an accessible way

SOYA IS SAFE AND HEALTHY (2021). Article around new report on soya and health

The Truth About Soya (2020). 60 mins webinar with Mark Messina exploring the health of soya

Sustainable Healthy Eating – What Does this Really Look Like? (2019) – 60 mins webinar with Dr Fabrice Declerck and RD Elphee Medici

Sustainable Diets – BDA One Blue Dot Webinar (2019) – 60 mins webinar with Tom Embury, Clare Pettinger and Lynne Garton